SARS Spike Monoclonal

SARS Spike Monoclonal

  • Name
  • Description
  • Cat#
  • Pricings
  • Quantity
  • SARS Spike Monoclonal

  • SARS-Spike protein, Monoclonal Antibody
  • ANT-179
  • Shipped with Ice Packs

Catalogue number



Mouse antibody Monoclonal.


SARS Coronavirus is an enveloped virus containing three outer structural proteins, namely the membrane (M), envelope (E), and spike (S) proteins. Spike (S)-glycoprotein of the virus interacts with a cellular receptor and mediates membrane fusion to allow viral entry into susceptible target cells. Accordingly, S-protein plays an important role in virus infection cycle and is the primary target of neutralizing antibodies.
It has recently been shown that SARS (severe acute respiratory syndrome) is caused by a human coronavirus. Human coronaviruses are the major cause of upper respiratory tract illness, such as the common cold, in humans. Coronaviruses are positive-stranded RNA viruses, featuring the largest viral RNA genomes known to date (27-31 kb). The first step in coronavirus infection is binding of the viral spike protein, a 139-kDa protein, to certain receptors on host cells. The spike protein is the main surface antigen of the coronavirus. The glycosilated spike protein (as well as the nucleocapsid protein) can be detected in infected cell culture supernatants with antisera from SARS patients.


0.5mg/ml, PBS, 0.2% gelatin and 0.05% sodium azide.


Mouse IgG1 kappa.


The antibody was developed using a synthetic peptide from the putative SARS Spike glycoprotein (Genbank accession no.NP_828851) corresponding to amino acids 19-45.


This monoclonal antibody can be used for detection of SARS Nucleocapsid protein in western blot analysis at 1-3 ug/ml, Immunocytochemistry and Immunofluorescence.


Store at 4C, stable for 2 weeks. For long-term storage, store at -20C.

Safety Data Sheet


Prospec's products are furnished for LABORATORY ESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
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