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CoV Spike Bovine

CoV Spike Bovine

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  • Quantity
  • CoV Spike Bovine

  • Mouse Anti Bovine Coronavirus Spike Monoclonal
  • ANT-755
  • Shipped with Ice Packs

Catalogue number

ANT-755

Type

Mouse antibody Monoclonal.

Introduction

SARS Coronavirus is an enveloped virus containing three outer structural proteins, namely the membrane (M), envelope (E), and spike (S) proteins. Spike (S)-glycoprotein of the virus interacts with a cellular receptor and mediates membrane fusion to allow viral entry into susceptible target cells. Accordingly, S-protein plays an important role in virus infection cycle and is the primary target of neutralizing antibodies.
It has recently been shown that SARS (severe acute respiratory syndrome) is caused by a human coronavirus. Human coronaviruses are the major cause of upper respiratory tract illness, such as the common cold, in humans. Coronaviruses are positive-stranded RNA viruses, featuring the largest viral RNA genomes known to date (27-31 kb). The first step in coronavirus infection is binding of the viral spike protein, a 139-kDa protein, to certain receptors on host cells. The spike protein is the main surface antigen of the coronavirus. The glycosilated spike protein (as well as the nucleocapsid protein) can be detected in infected cell culture supernatants with antisera from SARS patients.

Formulation

1mg/ml in 1X PBS pH-7.2 & 0.01% NaN3.

Isotype

IgG1 

Immunogen

The antibody was developed using purified bovine coronavirus. (eptopoe not mapped)

Applications

This Bovine Coronavirus Spike monoclonal antibody can be used in WB and ELISA

Stability

Store at 4C, stable for 2 weeks. For long-term storage, store at -20C.

Safety Data Sheet

Usage

Prospec's products are furnished for LABORATORY ESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
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