CFB-b Human

CFB-b Human

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  • CFB-b Human

  • Complement Factor B Fragment b Human
  • PRO-2736
  • Shipped with Ice Packs

Catalogue number



Complement factor B (EC:, C3/C5 convertase, Glycine-rich beta glycoprotein, GBG, PBF2, Properdin factor B, Complement factor B Ba fragment, Complement factor B Bb fragment, CFB, Complement Factor B, BFD, AHUS4, BF, BFD, CFAB, FB, FBI12, H2-Bf.


Complement Factor B, also known as CFB, encodes complement factor B which is a component of the alternative pathway of complement activation. Factor B circulates in the blood as a single chain polypeptide. Once the alternative pathway is activated it is cleaved by complement factor D yielding the noncatalytic chain Ba and the catalytic subunit Bb. The active subunit Bb is a serine protease which connects with C3b to form the alternative pathway C3 convertase. Also, Bb is involved in the proliferation of preactivated B lymphocytes, while Ba inhibits their proliferation.


CFB-b Human produced in Human Plasma having a molecular mass of 33 kDa.


Human Plasma.

Physical Appearance

Sterile filtered solution.


CFB-b solution (1mg/ml) contains Phosphate-buffered saline, pH 7.3.


CFB-b Human is stable at 4°C if entire vial will be used within 2-4 weeks.
Store, frozen below -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles.


Greater than 95.0% as determined by SDS-PAGE.

Human Virus Test

Plasma from each donor has been tested and found negative for antibody to HIV-1,

Safety Data Sheet


ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
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