prospec
CFB-a Human

CFB-a Human

  • Name
  • Description
  • Cat#
  • Pricings
  • Quantity
  • CFB-a Human

  • Complement Factor B Fragment a Human
  • PRO-2735
  • Shipped with Ice Packs

Catalogue number

PRO-2735

Synonyms

Complement factor B (EC:3.4.21.47), C3/C5 convertase, Glycine-rich beta glycoprotein, GBG, PBF2, Properdin factor B, Complement factor B Ba fragment, Complement factor B Bb fragment, CFB, Complement Factor B, BFD, AHUS4, BF, BFD, CFAB, FB, FBI12, H2-Bf.

Introduction

Complement Factor B, also known as CFB, encodes complement factor B which is a component of the alternative pathway of complement activation. Factor B circulates in the blood as a single chain polypeptide. Once the alternative pathway is activated it is cleaved by complement factor D yielding the noncatalytic chain Ba and the catalytic subunit Bb. The active subunit Bb is a serine protease which connects with C3b to form the alternative pathway C3 convertase. Also, Bb is involved in the proliferation of preactivated B lymphocytes, while Ba inhibits their proliferation.

Description

CFB-a Human produced in Human Plasma having a molecular mass of 33 kDa.

Source

Human Plasma.

Physical Appearance

Sterile filtered solution.

Formulation

CFB-a solution (1mg/ml) contains Phosphate-buffered saline, pH 7.3.

Stability

CFB-a Human is stable at 4°C if entire vial will be used within 2-4 weeks.
Store, frozen below -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles.

Purity

Greater than 95.0% as determined by SDS-PAGE.

Human Virus Test

Plasma from each donor has been tested and found negative for antibody to HIV-1,
HIV-2, HCV and HBSAG.

Safety Data Sheet

Usage

ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
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