- Name
- Description
- Cat#
- Pricings
- Quantity
Catalogue number
PRO-460
Synonyms
B-cell lymphoma 6 protein, BCL-6, Zinc finger protein 51, LAZ-3 protein, BCL-5, Zinc finger and BTB domain-containing protein 27, BCL6, BCL5, LAZ3, ZBTB27, ZNF51, BCL6A.
Introduction
Bcl-6 proto-oncogene product (a Kruppel-type zinc-finger protein) is mainly expressed in normal germinal center B cells and related lymphomas. Bcl-6 is involved in chromosome rearrangements at 3q27 in non-Hodgkin’s lymphomas and Bcl-6 rearrangements have been detected in 33%-45% of diffuse large B cell lymphomas. Bcl-6 has been detected immunohistochemically in follicular lymphomas, diffuse large B cell lymphomas, Burkitt’s lymphomas and in nodular, lymphocyte predominant Hodgkin’s disease.
Description
Bcl-6 Human Recombinant (aa 1-150) expressed in E.coli, shows a 43kDa band on SDS-PAGE (Including GST tag).
The Bcl-6 is purified by proprietary chromatographic techniques.
The Bcl-6 is purified by proprietary chromatographic techniques.
Source
Escherichia Coli.
Physical Appearance
Sterile Filtered clear solution.
Formulation
Bcl-6 protein in 50mM Tris-HCl, pH7.5 and 10mM L-glutathione (reduced).
Stability
Store vial at -20°C to -80°C. When stored at the recommended temperature, this protein is stable for 12 months.
Please prevent freeze-thaw cycles.
Please prevent freeze-thaw cycles.
Safety Data Sheet
Usage
Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.