prospec

VAMP2 (1-94) Human

  • Name
  • Description
  • Pricings
  • Quantity
  • VAMP2 (1-94) Human
  • Synaptobrevin-2 (1-94 a.a) Human Recombinant
  • Shipped with Ice Packs

Catalogue number

PRO-2457

Synonyms

Vesicle Associated Membrane Protein 2, Synaptobrevin 2, VAMP-2, SYB2, Vesicle-Associated Membrane Protein 2, Synaptobrevin-2, Vesicle-associated membrane protein 2.

Introduction

Synaptobrevin 2 which is an 18 kDa integral membrane protein localized to the cytoplasmic surface of synaptic vesicle, consists of a proline-rich N-terminal region, a highly conserved hydrophilic domain, followed by a transmembrane anchor and a C-terminal. Synaptobrevin 2 is predominantly expressed in Langerhans islets and glomerular cells. The N-terminal domain of the protein (residues 1-89) forms a specific SNARE complex with the target membrane-associated t- or Q-SNAREs syntaxin 1 and SNAP-25.

Description

VAMP2 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 118 amino acids (1-94 a.a) and having a molecular mass of 12.8kDa.
VAMP2 is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

Source

Escherichia Coli.

Physical Appearance

Sterile Filtered colorless solution.

Formulation

VAMP2 protein solution (0.5mg/ml) containing Phosphate buffered saline (pH 7.4) and 10% Glycerol 0.1mM PMSF.

Stability

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles.

Amino acid sequence

MGSSHHHHHH SSGLVPRGSH MGSHMSATAA TAPPAAPAGE GGPPAPPPNL TSNRRLQQTQ AQVDEVVDIM RVNVDKVLER DQKLSELDDR ADALQAGASQ FETSAAKLKR KYWWKNLK.

Purity

Greater than 95.0% as dtermined by SDS-PAGE.

Usage

ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
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