TPMT Antibody

TPMT Antibody

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  • Description
  • Cat#
  • Pricings
  • Quantity
  • TPMT Antibody

  • Thiopurine S-methyltransferase, Mouse Anti Human
  • ANT-055
  • Shipped with Ice Packs

Catalogue number



TPMT, Thiopurine S-methyltransferase, EC, Thiopurine methyltransferase.


Mouse Anti Human Monoclonal.


TPMT, thiopurine S-methyltransferase, is a cytosolic enzyme that metabolizes thiopurine drugs via S-adenosyl-L-methionine as the S-methyl donor and S-adenosyl-L-homocysteine as a byproduct. TPMT activity exhibits autosomal codominant genetic polymorphism, and patients inheriting TPMT-deficiency are at high risk of potentially fatal hematopoietic toxicity.




Anti-human TPMT mAb, is derived from hybridization of mouse FO myeloma cells with spleen cells from BALB/c mice immunized with recombinant human TPMT amino acids 1-245 purified from E. coli.

Ig Subclass

Mouse IgG1 heavy chain and k light chain.

Purification Method

TPMT antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.


1mg/ml containing PBS, pH-7.4, & 0.1% Sodium Azide.

Storage Procedures

For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

Stability / Shelf Life

12 months at -20°C. 1 month at 4°C.


TPMT antibody has been tested by ELISA, Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended dilution range for Western blot analysis is 1:1,000.

Safety Data Sheet


ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
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