Treponema TP0453

Outer membrane protein TP0453, 30kLP, TP_0453, TPANIC_0453

Tp0453 is a carrier of lipids and glycolipids during outer membrane. Tp045 is hypothesized to be a new type of bacterial outer membrane protein, which reduces T.pallidum  outer membrane permeability to nutrients while remaining inaccessible to antibodies.  Tp0453 exhibited 100% specificity and sensitivity in reaction with syphilis patients’ sera, giving negative result with Lyme disease, relapsing-fever or leptospirosis patients’ sera.

Recombinant Treponema pallidum Outer Membrane Protein TP0453 has a Mw of 26kDa, and was purified from E. coli.
The Recombinant Treponema pallidum Outer Membrane Protein TP0453 is fused to 6 amino acid His tag at its C terminal and purified by proprietary chromatographic technique.

Escherichia Coli.

Sterile Filtered clear solution.

Treponema TP0453 solution contains 25mM K₂CO₃ with PBS.

Store at 4°C if entire vial will be used within 2-4 weeks.
Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles.

Protein is >95% pure as determined by SDS-PAGE (coomassie staining).

Rapid test, Immunoassay.

SDS