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TNNI3 Human, His

TNNI3 Human, His

  • Name
  • Description
  • Cat#
  • Pricings
  • Quantity
  • TNNI3 Human, His

  • Cardiac Troponin-I Human Recombinant, His Tag
  • PRO-2266
  • Shipped with Ice Packs

Catalogue number

PRO-2266

Synonyms

Troponin I cardiac muscle, Cardiac troponin I, TNNI3, TNNC1, CMH7, RCM1, cTnI, CMD2A, MGC116817.

Introduction

Troponin I (TnI), troponin T (TnT) and troponin C (TnC) form the troponin complex of the thin filaments of striated muscle. TnI is acts as the inhibitory subunit by blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains 3 genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. The TNNI3 gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in the TNNI3 gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM).

Description

Recombinant Human TNNI3 protein produced in E.Coli is a full length protein containing a total of 210 amino acids and fused to a 6 His Tag at C-terminus, migrating as a 27kDa band on SDS-PAGE.
Purified by proprietary chromatographic technique.

Source

Escherichia Coli.

Physical Appearance

Sterile Filtered clear solution.

Formulation

TNNI3 protein solution in PBS and 25mM arginine.

Purity

Protein is >95% pure as determined by 12% PAGE (coomassie staining).

Stability

TNNI3 although stable at 4°C for 1 week, should be stored below -18°C. 
Please prevent freeze thaw cycles.

Safety Data Sheet

Usage

Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
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