- Name
- Description
- Cat#
- Pricings
- Quantity
Catalogue number
PRO-2325
Synonyms
CD352, KALI, KALIb, Ly108, NTB-A, NTBA, Activating NK receptor, SLAM family member 6.
Introduction
SLAM family member 6 (SLAMF6) is a member of the SLAM family of immune cell receptors. SLAMF6 is a unique receptor on T cells which, when triggered potentiates T cell expansion in a CD28-independent manner. SLAMF6 has a high expression on NK-, T-, and B cells. SLAMF6 exhibits homotypic interactions and can connect with adaptor molecules such as SAP to alter immune cell function.
Description
Recombinant Human SLAM Family Member 6/SLAMF6 is produced HEK cells. The target protein is expressed with sequence (Leu28-Lys225) of Human SLAMF6 fused with a polyhistidine tag at the C-terminus.
Source
HEK 293 cells.
Physical Appearance
Sterile Filtered White lyophilized (freeze-dried) powder.
Formulation
Lyophilized from a (0.2µM) filtered solution containing 20mM PB and 150mM NaCl, pH 7.2.
Solubility
It is recommended to reconstitute the lyophilized SLAMF6 in sterile 1xPBS not less than 100µg/ml, which can then be further diluted to other aqueous solutions.
Stability
Lyophilized SLAMF6 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution SLAMF6 should be stored at 4°C between 2-7 days and for future use below -18°C.
Please prevent freeze-thaw cycles.
Please prevent freeze-thaw cycles.
Purity
Greater than 95.0% as determined by SDS-PAGE.
Amino acid sequence
LMVNGILGESVTLPLEFPAGEKVNFITWLFNETSLAFIVPHETKSPEIHVTNPKQG
KRLNFTQSYSLQLSNLKMEDTGSYRAQISTKTSAKLSSYTLRILRQLRNIQVTNHS
QLFQNMTCELHLTCSVEDADDNVSFRWEALGNTLSSQPNLTVSWDPRISSEQD
YTCIAENAVSNLSFSVSAQKLCEDVKIQYTDTKVDHHHHHH.
KRLNFTQSYSLQLSNLKMEDTGSYRAQISTKTSAKLSSYTLRILRQLRNIQVTNHS
QLFQNMTCELHLTCSVEDADDNVSFRWEALGNTLSSQPNLTVSWDPRISSEQD
YTCIAENAVSNLSFSVSAQKLCEDVKIQYTDTKVDHHHHHH.
Usage
Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. They may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.