prospec

Seprase Human

  • Name
  • Description
  • Pricings
  • Quantity
  • Seprase Human
  • Fibroblast Activation Protein Alpha Human Recombinant
  • Shipped with Ice Packs

Catalogue number

ENZ-465

Synonyms

170 kDa melanoma membrane-bound gelatinase, DKFZp686G13158, DPPIV, FAPA, Fibroblast activation protein alpha, Integral membrane serine protease, Seprase, FAP.

Introduction

Seprase is a dual specificity serine protease expressed in reactive human tumor stromal fibroblasts. Seprase is a homodimeric integral membrane gelatinase, which is part of the serine protease family. Seprase is expressed in reactive stromal fibroblasts of epithelial cancers, granulation tissue of healing wounds, and malignant cells of bone and soft tissue sarcomas. Seprase protein has a role in the control of fibroblast growth or epithelial-mesenchymal interactions throughout development, tissue repair, and epithelial carcinogenesis.

Description

Seprase Human Recombinant produced in E.Coli is single, a non-glycosylated, Polypeptide chain containing 203 amino acids (559-761 a.a.) and having a total Mw of 48kDa. Seprase is fused to a GST tag and is purified by proprietary chromatographic techniques.

Source

Escherichia Coli.

Physical Appearance

Sterile Filtered clear solution.

Formulation

Seprase is supplied in 50mM Tris-Acetate, pH-7.5, 1mM EDTA and 20% Glycerol.

Stability

Store at 4°C if entire vial will be used within 2-4 weeks.
Store, frozen at -20°C for longer periods of time.
Please avoid freeze thaw cycles.

Safety Data Sheet

Usage

ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
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