Human Retinol Binding Protein, also known as RBP, is responsible for transporting and binding vitamin A. Human RBP has a binding site for 1 molecule of retinol and circulates in the plasma together with prealbumin as a protein complex. The prealbumin binding prevents greater glomerular losses of the human RBP. Only the retinol-free form of the RBP, which has no affinity for prealbumin, undergoes glomerular filtration unhindered as a result of its low Mw. Human RBP is re-absorbed by the tubular cells and catabolized there.
Human Retinol Binding Protein Native produced in urine from the patients with renal tubular proteinuria having a molecular mass of approximately 21kD.
Urine from the patients with renal tubular proteinuria.
Sterile Filtered White lyophilized (freeze-dried) powder.
The protein was lyophilized (0.2 µm filtered) from 20mM NH4HCO3.
It is recommended to reconstitute the lyophilized RBP Human in phosphate buffer containing 0.15M NaCl.
RBP Human although stable at room temperature for 3 weeks, should be stored between 2-8°C.
Greater than 96.0%.
Human Virus Test
Starting material donor has been tested and certified negative for antibodies to HIV-1, HIV-2, HCV, HBSAG and Syphilis.