prospec

Reductase

  • Name
  • Description
  • Pricings
  • Quantity
  • AKR1A1 Human
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  • Aldo-Keto Reductase Family 1 Member A1 Human Recombinant
  • Shipped with Ice Packs
  • AKR1B1 Human
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  • Aldose Reductase Human Recombinant
  • Shipped with Ice Packs
  • AKR1B1 Mouse
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  • Aldose Reductase Mouse Recombinant
  • Shipped with Ice Packs
  • AKR1B10 Human
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  • Aldo-Keto Reductase Family 1 Member B10 Human Recombinant
  • Shipped with Ice Packs
  • AKR1C1 Human
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  • Aldo-Keto Reductase Family 1 Member C1 Human Recombinant
  • Shipped with Ice Packs
  • AKR1C3 Human
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  • Aldo-Keto Reductase Family 1 Member C3 Human Recombinant
  • Shipped with Ice Packs
  • AKR1C4 Human
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  • Aldo-Keto Reductase Family 1 Member C4 Human Recombinant
  • Shipped with Ice Packs
  • AKR1D1 Human
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  • Aldo-Keto Reductase Family 1 Member D1 Human Recombinant
  • Shipped with Ice Packs
  • AKR1D1 Human, His
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  • Aldo-Keto Reductase Family 1 Member D1 Human Recombinant, His Tag
  • Shipped with Ice Packs
  • AKR7A2 Human
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  • Aldo-Keto Reductase Family 7 Member A2 Human Recombinant
  • Shipped with Ice Packs
  • AKR7A3 Human
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  • Aldo-Keto Reductase Family 7 Member A3 Human Recombinant
  • Shipped with Ice Packs
  • BLVRA Human
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  • Biliverdin Reductase A Human Recombinant
  • Shipped with Ice Packs
  • BLVRB Human
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  • Biliverdin Reductase B Human Recombinant
  • Shipped with Ice Packs
  • BLVRB Mouse
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  • Biliverdin Reductase B Mouse Recombinant
  • Shipped with Ice Packs
  • CBR1 Human
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  • Carbonyl Reductase-1 Human Recombinant
  • Shipped with Ice Packs
  • CBR3 Human
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  • Carbonyl Reductase-3 Human Recombinant
  • Shipped with Ice Packs
  • CBR4 Human
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  • Carbonyl Reductase-4 Human Recombinant
  • Shipped with Ice Packs
  • CRYZL1 Human
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  • Quinone Oxidoreductase-like Protein 1 Human Recombinant
  • Shipped with Ice Packs
  • CYB5R1 Human
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  • Cytochrome B5 Reductase 1 Human Recombinant
  • Shipped with Ice Packs
  • CYB5R2 Human
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  • Cytochrome B5 Reductase 2 Human Recombinant
  • Shipped with Ice Packs
  • CYSH E.Coli
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  • Phosphoadenosine phosphosulfate reductase E.Coli Recombinant
  • Shipped with Ice Packs
  • DCXR Human
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  • Dicarbonyl/L-Xylulose Reductase Human Recombinant
  • Shipped with Ice Packs
  • DCXR Human, Bioactive
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  • Dicarbonyl/L-Xylulose Reductase Human Recombinant, Bioactive
  • Shipped with Ice Packs
  • DECR1 Human
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  • 2,4-Dienoyl CoA Reductase 1 Human Recombinant
  • Shipped with Ice Packs
  • DECR2 Human
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  • 2,4-Dienoyl CoA Reductase 2 Human Recombinant
  • Shipped with Ice Packs
  • DHFR Human
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  • Dihydrofolate Reductase Human Recombinant
  • Shipped with Ice Packs
  • DHFR Mouse
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  • Dihydrofolate Reductase Mouse Recombinant
  • Shipped with Ice Packs
  • DHRS4 Human
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  • Dehydrogenase/Reductase Member 4 Human Recombinant
  • Shipped with Ice Packs
  • DHRS9 Human
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  • Dehydrogenase/Reductase Member 9 Human Recombinant
  • Shipped with Ice Packs
  • DsbA
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  • Disulfide Oxidoreductase Recombinant
  • Shipped at Room temp.
  • GMPR Human
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  • Guanosine Monophosphate Reductase Human Recombinant
  • Shipped with Ice Packs
  • GMPR2 Human
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  • Guanosine Monophosphate Reductase 2 Human Recombinant
  • Shipped with Ice Packs
  • GOR E.Coli
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  • Glutathione Oxidoreductase E.Coli Recombinant
  • Shipped with Ice Packs
  • GRHPR Human
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  • Glyoxylate Reductase/Hydroxypyruvate Reductase Human Recombinant
  • Shipped with Ice Packs
  • GSR Human
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  • Glutathione Reductase Human Recombinant
  • Shipped with Ice Packs
  • KDSR Human
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  • 3-Ketodihydrosphingosine Reductase Human Recombinant
  • Shipped with Ice Packs
  • MECR Human
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  • Mitochondrial Trans-2-Enoyl-CoA Reductase Human Recombinant
  • Shipped with Ice Packs
  • MSRA E.Coli
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  • Methionine Sulfoxide Reductase A E.Coli Recombinant
  • Shipped with Ice Packs
  • MSRA Human
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  • Methionine Sulfoxide Reductase A Human Recombinant
  • Shipped with Ice Packs
  • MSRB E.Coli
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  • Methionine Sulfoxide Reductase B E.Coli Recombinant
  • Shipped with Ice Packs
  • MSRB2 Human
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  • Methionine Sulfoxide Reductase B2 Human Recombinant
  • Shipped with Ice Packs
  • MSRB3 Human
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  • Methionine Sulfoxide Reductase B3 Human Recombinant
  • Shipped with Ice Packs
  • NFNB E.Coli
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  • Dihydropteridine Reductase E.Coli Recombinant
  • Shipped with Ice Packs
  • PECR Human
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  • Peroxisomal Trans-2-enoyl-CoA Reductase Human Recombinant
  • Shipped with Ice Packs
  • PTGR1 Human
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  • Prostaglandin Reductase 1 Human Recombinant
  • Shipped with Ice Packs
  • PTGR2 Human
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  • Prostaglandin Reductase 2 Human Recombinant
  • Shipped with Ice Packs
  • PYCR1 Human
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  • Pyrroline-5-Carboxylate Reductase 1 Human Recombinant
  • Shipped with Ice Packs
  • PYCR2 Human
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  • Pyrroline-5-Carboxylate Reductase 2 Human Recombinant
  • Shipped with Ice Packs
  • PYCRL Human
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  • Pyrroline-5-Carboxylate Reductase Like Human Recombinant
  • Shipped with Ice Packs
  • QDPR Human
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  • Quinoid Dihydropteridine Reductase Human Recombinant
  • Shipped with Ice Packs
  • RRM2 Human
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  • Ribonucleotide Reductase M2 Human Recombinant
  • Shipped with Ice Packs
  • SPR Human
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  • Sepiapterin Reductase Human Recombinant
  • Shipped with Ice Packs
  • SPR Mouse
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  • Sepiapterin Reductase Mouse Recombinant
  • Shipped with Ice Packs
  • TP53I3 Human
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  • Tumor Protein p53 Inducible Protein 3 Human Recombinant
  • Shipped with Ice Packs
  • TRXR E.Coli
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  • Thioredoxin Reductase E.Coli Recombinant
  • Shipped with Ice Packs
  • TrxR Yeast
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  • Thioredoxin Reductase (NADPH) Yeast Recombinant
  • Shipped at Room temp.
  • TXNRD1 Human
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  • Thioredoxin Reductase 1 Human Recombinant
  • Shipped with Ice Packs
  • TXNRD1 Human 161-649 a.a.
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  • Thioredoxin Reductase 1 161-649 a.a. Human Recombinant
  • Shipped with Ice Packs
  • TXNRD3NB Human
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  • Thioredoxin Reductase 3 Neighbor Human Recombinant
  • Shipped with Ice Packs
  • WWOX Human
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  • WW Domain Containing Oxidoreductase Human Recombinant
  • Shipped with Ice Packs

About Reductase:

A reductase is an enzyme characterized as catalyzing a reduction reaction, making it one of the most significant enzymes in intra and extracellular biosynthesis of metal nanoparticles in fungus.

Reductase Structure
Examples of reductase enzymes include 5a-Reductase, 5b-Reductase, Dihydrofolate reductase, HMG-CoA reductase, Methemoglobin reductase, Ribonucleotide reductase, Thioredoxin reductase, E.coli nitroductase, and Methylenetetrahydrofolate reductase.
Quinone reductases are a large family of enzymes, of which NQO1 and NQO2 are the most prominent features, that catalyze the reduction of quinones to hydroquinones. The FAD-containing homodimers share many similar properties, although the their interactions with pyridine nucleotide cofactors and inhibitors are vastly different.
The structure of each enzyme within the reductase family is unique to the others. The transmembrane respiratory nitrate reductase, for example, consists of an alpha, 1 beta and 2 gamm while it carries an Enzyme Commission (EC) number of 1.7.99.4 and a CAS number of 37256-45-4. Meanwhile, the coding region for the reductase mRNA is present in exons 2 through 20 while the mRNA for HMG CoA reductase can differ vastly due to heterogeneity in both the 3′ and 5′ untranslated regions.

Reductase Function and Mechanisms
Enzyme inhibitors of the HMGCoA reductase boast antifungal activity against some yeast species while they only show very low toxicity levels towards mammalian cells, including human cells. Either HMG1, which is responsible for 83% of the protein, or HMG2 genes can provide viability but the deletion of both genes is lethal.
If the HMGCoA reductase is overexpressed, it will grow a resistance to inhibitors while underexpression can bring an increased sensitivity. Both HMG1 and HMG2 reductase activity have been shown to regulate the growth of certain yeast strains, suggesting it can be used as a microbiological screen to identify inhibitors of the human enzyme .
Aldehyde reductase activity has also been found in the spruce budworm. When both NAD(P)H and the gland homogenate are present, aldehyde can be broken down to a fatty alcohol. N2O reductase, which is found in various denitrifiers is responsible for performing the last step of denitrification.

Reductase Interactions
The reductase group of enzymes are found in mammals as well as humans, interacting with various drugs to increase, reduce, or even destruct proteins and cells. Roughyl 70% of mRNA molecules found at sites with a 25> bp region are initiated while the 5’ end of the human reductase gene is isolated and utilized to map RNA transcripts. In human fibroblasts, utilization spans a region of about 25 nucleotides.
Single nucleotide polymorphisms within NQO1 and NQO2 can reduce the levels of functional proteins within the human body. Due to the high levels of the enzymes, along with their protein–protein interactions relating to the p53 tumor suppressor, have seen them become molecular targets in cancer treatments. Furthermore, their ability to bioactivate with an array of antitumor drugs has been noted.
Meanwhile, the ferredoxin reductase expression, which is is two orders of magnitude higher in steroidogenic tissues, contains two homologous genes (FDX1 and FDX2) that provides the synthesis of iron–sulfur clusters while the interaction domain consists of residues 56–90.