prospec

LAMP1 Human

  • Name
  • Description
  • Pricings
  • Quantity
  • LAMP1 Human
  • Lysosomal-Associated Membrane Protein Human 1 Recombinant
  • Shipped with Ice Packs

Catalogue number

PRO-2478

Synonyms

Lysosome-associated membrane glycoprotein 1, LAMP1, CD107a, LAMPA, LGP120, LAMP-1, CD107 antigen-like family member A.

Introduction

Lysosomal-Associated Membrane Protein 1 (LAMP1) is a part of the LAMP family.  LAMP1 is a membrane protein which is expressed in the endosome-lysosome membranes of cells and is implicated in tumor cell metastasis. A glycoform of LAMP1 is expressed on the surface of activated macrophages and promotes T cell costimulation and a Th1 biased immune response.  LAMP1 is also found on the plasma membrane during the activation of NK cells, CD8 & T cells, monocytes, basophils, and platelets.

Description

LAMP1 produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 363 amino acids (29-382a.a.) and having a molecular mass of 39.4kDa. (Molecular size on SDS-PAGE will appear at approximately 57-70kDa).
LAMP1 is expressed with a 9 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques.

Source

Sf9, Baculovirus cells.

Physical Appearance

Sterile filtered colorless solution.

Formulation

LAMP1 protein solution (1mg/ml) contains phosphate buffered saline (pH7.4) and 10% glycerol.

Stability

Store at 4°C if entire vial will be used within 2-4 weeks.
Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles.

Purity

Greater than 90.0% as determined by SDS-PAGE.

Amino acid sequence

ADPAMFMVKN GNGTACIMAN FSAAFSVNYD TKSGPKNMTF DLPSDATVVL NRSSCGKENT SDPSLVIAFG RGHTLTLNFT RNATRYSVQL MSFVYNLSDT HLFPNASSKE IKTVESITDI RADIDKKYRC VSGTQVHMNN VTVTLHDATI QAYLSNSSFS RGETRCEQDR PSPTTAPPAP
PSPSPSPVPK SPSVDKYNVS GTNGTCLLAS MGLQLNLTYE RKDNTTVTRL LNINPNKTSA SGSCGAHLVT LELHSEGTTV LLFQFGMNAS SSRFFLQGIQ LNTILPDARD PAFKAANGSL RALQATVGNS YKCNAEEHVR VTKAFSVNIF KVWVQAFKVE GGQFGSVEEC LLDENSMHHH
HHH

Safety Data Sheet

Usage

ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
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