HIV-1 NEF Biotin

HIV-1 NEF Biotin

  • Name
  • Description
  • Cat#
  • Pricings
  • Quantity
  • HIV-1 NEF Biotin

  • HIV-1 nef Recombinant Biotin Labeled
  • HIV-009
  • Shipped with Ice Packs

Catalogue number



HIV-1 Nef is anessential factor for efficient viral replication and pathogenesis and therefore is produced shortly after virus infection. HIV-1 Nef is also facilitates virus replication and enhances virions infectivity. Nef exerts pleiotropic effects: decreases cell surface CD4 antigen by interacting with the Src family kinase LCK, down-modulates surface MHC-I molecules and protects the infected cell from apoptosis in order to keep it alive until the next virus generation is mature. Nef protein bypasses host T-cell signaling byinducing a trascriptional program almost identical to that of anti-CD3 cell activation.


Recombinant HIV-1 nef Biotin Labeled is a full length protein produced in E.coli and having a molecular mass of 27kDa. HIV-1 nef Biotin is purified by proprietary chromatographic technique.


Escherichia Coli.

Physical Appearance

Sterile Filtered clear solution.


HIV-1 nef Biotin protein solution containing PBS & 0.05%(v/v) glycerol.


HIV-1 nef Biotin although stable at 4°C for 1 week, should be stored below -18°C.
Please prevent freeze thaw cycles


Greater than 90.0% as determined by SDS-PAGE.


Western Blotting, SDS Page

Safety Data Sheet


ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. They may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
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