prospec

HCV Core 169aa

  • Name
  • Description
  • Pricings
  • Quantity
  • HCV Core 169aa
  • Hepatitis C Virus Nucleocapsid (core) 169aa Recombinant
  • Shipped with Ice Packs

Catalogue number

HCV-012

Introduction

HCV is a small 50nm, enveloped, single-stranded, positive sense RNAvirus in the family Flaviviridae.
HCV has a high rate of replication with approximately one trillion particles produced each day in an infected individual. Due to lack of proofreading by the HCV RNA polymerase, the HCV has an exceptionally high mutation rate, a factor that may help it elude the host's immune response. Hepatitis C virus is classified into six genotypes(1-6) with several subtypes within each genotype. The preponderance and distribution of HCV genotypes varies globally. Genotype is clinically important in determining potential response to interferon-based therapy and the required duration of such therapy. Genotypes 1 and 4 are less responsive to interferon-based treatment than are the other genotypes (2, 3, 5 and 6).

Description

Recombinant HCV core protein genotype 1b produced in E.Coli, comprised of the large core peptide containing 169 a.a., fused to a 6xHis tag at C-terminus, having a total Mw of 25.4kDa and pI of 11.02. Recombinant HCV core protein genotype 1b was purified by proprietary chromatographic techniques. 

Source

Escherichia Coli.

Physical Appearance

Sterile filtered colorless solution.

Formulation

Sterile filtered solution containing Phosphate saline buffer, 50mM arginine and 1M urea.

Stability

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles.

Purity

Greater than 95.0% as determined by SDS-PAGE.

Usage

ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
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