Caused by one of four closely related virus serotypes of the genus Flavivirus, family Flaviviridae, each serotype is sufficiently different that there is no cross-protection and epidemics caused by multiple serotypes (hyperendemicity) can occur. In cell culture experiments and mice Morpholino antisense oligos have shown specific activity against Dengue virus.
The E.Coli derived recombinant protein contains the NS1 Dengue Virus c-end Type-2 immunodominant regions.
Dengue protein is purified by proprietary chromatographic technique.
Dengue Protein is >90% pure as determined by 10% PAGE (coomassie staining).
20mM Tris-HCl pH 8.0, 8M urea & 60mM NaCl.
Amino acid sequence
LWSNGVLESE MVIPKNFAGP KSQHNNRPGY HTQTAGPWHL GKLEMDFDFC EGTTVVVTED CGNRGPSLRT TTASGKLITE WCCRSCTLPP LRYRGEDGCW YGMEIRPLKE KEENLVSSLV TAHHHHHH
Each laboratory should determine an optimum working titer for use in its particular application.
Dengue although stable at 4°C for 1 week, should be stored below -18°C.
Please prevent freeze thaw cycles.
Safety Data Sheet
Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. They may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.