C6 Human

C6 Human

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  • C6 Human

  • Complement C6 Human
  • PRO-2693
  • Shipped with Ice Packs

Catalogue number



Complement component C6, C6.


C6 is necessary for membrane attack complex formation and is activated by binding to recently-formed C5b at the cell membrane.Each pathway of complement activation generates proteolytic enzyme complexes which are bound to the target surface. These enzymes cleave a peptide bond in the larger alpha chain of C5 releasing C5a and activating C5b. Although C5b is unstable it remains bound to the activating complex for a few minutes during which it binds a single C6 from the surrounding fluid or it decays and is no longer capable of forming MAC. The C5b,6 complex may also remain connected to the C3/C5 convertase where the binding of a single C7 exposes a membrane-binding region and C5b,6,7 can enter into the bilipid layer of the target cell.


Human Complement C6 produced in Human plasma having a molecular mass of 105 kDa.


Human Plasma.

Physical Appearance

Sterile filtered solution.


C6 protein solution contains phosphate buffer saline, pH 7.2.


C6 Human is stable at 4°C if entire vial will be used within 2-4 weeks.
Store, frozen below -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles.


Greater than 90.0% as determined by SDS-PAGE.

Human Virus Test

Plasma from each donor has been tested and found negative for antibody to HIV-1, HIV-2, HCV and HBSAG.

Safety Data Sheet


ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
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