MYC, CMYC, C-MYS, V-MYC, P64.
Mouse Anti Human Monoclonal.
c-Myc is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of c-Myc have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene.
1mg/ml in PBS (after reconstitution).
Antibody is shipped lyophilized at ambient temperature.
Reconstitute with H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use.
By Western blot 1:2,000 dilution will yield a strong band in WB.
This antibody was produced in BALB/c mice.
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