- Name
- Description
- Cat#
- Pricings
- Quantity
Catalogue number
PRO-2479
Synonyms
Anti-Muellerian hormone, AMH, Muellerian-inhibiting substance, MIS, MIF.
Introduction
Anti-Mullerian Hormone also known as AMH is a member of the TGF-beta family. AMH is a glycoprotein which is produced by the Sertoli cells of the testis, causes regression of the Muellerian duct. AMH inhibits the growth of tumors derived from tissues of Muellerian duct origin. Moreover, AMH participates in Leydig cell differentiation and function in addition to follicular development in adult females.
Description
AMH Human Recombinant produced in E. coli is a single, non-glycosylated polypeptide chain (a.a 452-560) containing 118 amino acids including a 9 a.a N-terminal His tag. The total molecular mass is 12.8kDa (calculated).
Source
Escherichia Coli.
Physical Appearance
Formulation
AMH filtered (0.4 µm) and lyophilized in 1mM HCl and 5% (w/v) trehalose.
Solubility
It is recommended to add deionized water to prepare a working stock solution of approximately 0.5mg/ml and let the lyophilized pellet dissolve completely. AMH is not sterile! Please filter the product by an appropriate sterile filter before using it in the cell culture.
Stability
Store lyophilized protein at -20°C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted protein can be stored at 4°C for a limited period of time; it does not show any change after one week at 4°C.
Purity
Greater than 95.0% as determined by SDS-PAGE.
Amino acid sequence
MKHHHHHHAS AGATAADGPC ALRELSVDLR AERSVLIPET YQANNCQGVC GWPQSDRNPR YGNHVVLLLK MQARGAALAR PPCCVPTAYA GKLLISLSEE RISAHHVPNM VATECGCR
Safety Data Sheet
Usage
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. They may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.