Adaptor-Related Protein Complex

Adaptor-Related Protein Complex

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About Adaptor-Related Protein Complex:

The adaptor-related protein complex 2 (AP-2 complex) is a protein found in humans that is encoded by the AP2A1 gene. The gene is responsible for encoding the alpha 1 adaptin subunit of the AP-2 complex found in clathrin coated vesicles. They are vesicle coat components, involved in the formation of vesicles, as well as cargo selection.

Adaptor-Related Protein Complex Mechanism
Adaptor protein complexes help to transport cargo from one membrane compartment of the cell to another. In order to do this, they use other proteins by way of assistance, and it has always been assumed that there were 4 of these adaptor protein complexes present in eukaryotic cells - cells found in plants, animals, fungi, and protists. However, in recent times there has been the discovery of a 5th AP.

Adaptor-Related Protein Complex Function
AP-2 is typically the most widely studied, and it facilitates clathrin-mediated endocytosis of a wide-range of proteins. Proteins are essential for growth and maintenance, as well as sending messages to our body, and helping us grow and develop as human beings.
This is what makes adaptor proteins so important; they contain a selection of protein-being modules that help with the creation of larger signaling complexes. When certain, specific proteins link together, which grow cellular signals in order to provide a response from the cell to the environment.