prospec

VCAM1 Human

  • Name
  • Description
  • Pricings
  • Quantity
  • VCAM1 Human
  • Vascular Cell Adhesion Molecule 1 Human Recombinant
  • Shipped with Ice Packs

Catalogue number

PRO-386

Synonyms

Vascular cell adhesion protein 1, V-CAM 1, INCAM-100, CD106, VCAM1, L1CAM, MGC99561, DKFZp779G2333.

Introduction

VCAM1 is a member of the Ig superfamily. It is a cell surface sialoglycoprotein expressed by cytokine activated endothelium. VCAM-1 contains 6 or 7 immunoglobulin domains, and is expressed on both large and small vessels only after the endothelial cells are stimulated by cytokines. The protein has a number of functions including the regulation of leukocyte migration, leukocyte endothelial cell adhesion and signal transduction and may play a role in a number of inflammatory diseases (artherosclerosis and rheumatoid arthritis).

Description

VCAM1 Human Recombinant is expressed in E. coli containing 674 amino acids (a.a. 25-698) fused to an amino terminal hexahistidine tag, having a total MW of 78.8kDa.

Source

Escherichia Coli.

Formulation

VCAM1 is supplied in 10mM Tris-HCl (pH 8), 250mM NaCl, 0.5mM DTT, 1.5mM Cysteine, and 50% Glycerol.

Applications

VCAM1 can be used directly as a positive control in Western blotting, ELISA, immunoprecipitation and other immunological experiments. 
The biological activity of this product has not yet been tested.

Stability

Store at 4°C if entire vial will be used within 1-2 weeks. 
Store, frozen at -20°C for longer periods of time. 
Avoid multiple freeze-thaw cycles.

Purity

Greater than 95% as determined by SDS-PAGE.

References

Title: Novel Regulators of Fgf23 Expression and Mineralization in Hyp Bone
Publication: Molecular Endocrinology 23.9 (2009): 1505-1518.
Link: http://press.endocrine.org/doi/full/10.1210/me.2009-0085

Usage

Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
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