prospec

TUBB2B Antibody

  • Name
  • Description
  • Pricings
  • Quantity
  • TUBB2B Antibody
  • Tubulin beta-2B chain, Mouse Anti Human
  • Shipped with Ice Packs

Catalogue number

ANT-019

Synonyms

Tubulin beta-2B chain, TUBB2B, MGC8685, FLJ98847, bA506K6.1, DKFZp566F223, RP11-506K6.1.

Type

Mouse Anti Human Monoclonal.

Introduction

TUBB2B is a beta isoform of tubulin, which binds GTP and is a major component of microtubules. Numerous beta Tubulin isoforms have been characterized and are expressed in mammalian tissues. Tubulin binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain. TUBB2b is mostly expressed in developing neurons with a dominant expression during the critical steps of corticogenesis. In addition, TUBB2B is a new critical gene involved in neuronal migration. TUBB2B is present in the nuclei and nucleoplasm, Defects in the TUBB2B gene are a cause of asymmetric polymicrogyria.

Physical Appearance

Sterile Filtered clear solution.

Clone

PAT5B2AT.

Immunogen

Anti-human TUBB2b mAb, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with recombinant human TUBB2b amino acids 1-445 purified from E. coli.

Ig Subclass

Mouse IgG2a heavy chain and k light chain.

Purification Method

TUBB2b antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.

Formulation

1mg/ml containing PBS, pH-7.4, & 0.1% Sodium Azide.

Storage Procedures

For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

Stability / Shelf Life

12 months at -20°C. 1 month at 4°C.

Applications

TUBB2b antibody has been tested by ELISA, Western blot and Immunofluorescence analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended dilution range for Western blot analysis and Immunofluorescence is 1:250 ~ 500. Recommended starting dilution is 1:250.

Usage

ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
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