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SERPINB3 Human

SERPINB3 Human

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  • SERPINB3 Human

  • Serpin Peptidase Inhibitor, Clade B Member 3 Human Recombinant
  • PRO-2198
  • Shipped with Ice Packs

Catalogue number

PRO-2198

Synonyms

Serpin B3, Squamous cell carcinoma antigen 1, Protein T4-A, SCCA-1, Serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 3, SCCA1, Serine (Or Cysteine) Proteinase Inhibitor, Clade B (Ovalbumin), Member 3, Squamous Cell Carcinoma Antigen 1, Protein T4-A, SCCA-1, Serpin B3, HsT1196, SCCA-PD, T4-A , SCCA, SCC.

Introduction

Serpin Peptidase Inhibitor, Clade B Member 3, also known as SERPINB3 is a papain-like cysteine protease inhibitor which modulates the host immune response versus tumor cells. SERPINB3 is a protein coding gene which acts as an inhibitor of UV-induced apoptosis by suppressing the activity of c-Jun NH(2)-terminal kinase (JNK1).

Description

SERPINB3 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 413 amino acids (1-390 a.a) and having a molecular mass of 47kDa. 
SERPINB3 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

Source

Escherichia Coli.

Physical Appearance

Sterile Filtered colorless solution.

Formulation

SERPINB3 protein solution (0.5mg/ml) containing Phosphate buffered saline (pH7.4), 10% glycerol and 1mM DTT.

Stability

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. 
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). 
Avoid multiple freeze-thaw cycles.

Purity

Greater than 90.0% as determined by SDS-PAGE.

Amino acid sequence

MGSSHHHHHH SSGLVPRGSH MGSMNSLSEA NTKFMFDLFQ QFRKSKENNI FYSPISITSA LGMVLLGAKD NTAQQIKKVL HFDQVTENTT GKAATYHVDR SGNVHHQFQK LLTEFNKSTD AYELKIANKL FGEKTYLFLQ EYLDAIKKFY QTSVESVDFA NAPEESRKKI NSWVESQTNE KIKNLIPEGN IGSNTTLVLV NAIYFKGQWE KKFNKEDTKE EKFWPNKNTY KSIQMMRQYT SFHFASLEDV QAKVLEIPYK GKDLSMIVLL PNEIDGLQKL EEKLTAEKLM EWTSLQNMRE TRVDLHLPRF KVEESYDLKD TLRTMGMVDI FNGDADLSGM TGSRGLVLSG VLHKAFVEVT EEGAEAAAAT AVVGFGSSPT STNEEFHCNH PFLFFIRQNK TNSILFYGRF SSP.

Safety Data Sheet

SDS

Usage

ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
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