prospec

SERPINA3 Human

  • Name
  • Description
  • Pricings
  • Quantity
  • SERPINA3 Human
  • Alpha-1 AntiChymotrypsin Human
  • Shipped at Room temp.

Catalogue number

PRO-378

Synonyms

Alpha-1-antichymotrypsin, ACT, Cell growth-inhibiting gene 24/25 protein, SERPINA3, AACT, A1ACT, GIG24, GIG25, MGC88254.

Introduction

Alpha 1 ACT is an early-stage acute-phase plasma protein and a serpin that preferentially inactivates chymotrypsin, cathepsin G, and chymase. Alpha-1- ACT, a serine protease inhibitor, is tightly associated with amyloid plaques in Alzheimer's disease (AD) and in normal aged human and monkey brain.
Regulation of the serine proteases and serine protease inhibitors plays an important role in neuromuscular differentiation. Prostate specific antigen (PSA), a chymotrypsin-like serine protease, is predominantly complexed to Alpha-1-ACT.

Description

Human Alpha-1 AntiChymotrypsin produced from normal human serum having a molecular mass of 68kDa.

Source

Human Serum.

Physical Appearance

Sterile Filtered White lyophilized (freeze-dried) powder.

Formulation

Lyophilized from 0.02M NH4HCO3.

Solubility

It is recommended to reconstitute the lyophilized human A1ACT in phosphate buffer pH > 7.0 containing 0.15M NaCl.

Stability

Human SERPINA3 although stable at room temperature for 3 weeks, should be stored between 2-8°C.

Purity

Greater than 99.0%.

Human Virus Test

Starting material tested and found negative for HIV I & II antibodies, Hepatitis B surface antigen, and Hepatitis C antibodies.

Usage

Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
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