prospec

MESDC2 Human

  • Name
  • Description
  • Pricings
  • Quantity
  • MESDC2 Human
  • Mesoderm Development Candidate 2 Human Recombinant
  • Shipped with Ice Packs

Catalogue number

PRO-122

Synonyms

LDLR chaperone MESD, Mesoderm development candidate 2, Mesoderm development protein, Renal carcinoma antigen NY-REN-61, MESDC2, KIAA0081, MESD, BOCA.

Introduction

Mesoderm development candidate 2 (MESDC2) is required for formation of the primitive streak and mesoderm during embryogenesis. MESDC2 binds to the Wnt co-receptors LRP5 and LRP6 in the endoplasmic reticulum and is required for their proper folding and cell surface expression.

Description

MESDC2 Human Recombinant fused with a 21 amino acid His tag at N-terminus produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 222 amino acids (34-234 a.a.) and having a molecular mass of 24.9kDa (Molecular weight on SDS-PAGE will appear higher).
The MESDC2 is purified by proprietary chromatographic techniques.

Source

Escherichia Coli.

Physical Appearance

Sterile Filtered colorless solution.

Formulation

The MESDC2 solution (1 mg/ml) contains 20mM Tris-HCl buffer (pH8.0), 20% glycerol, 0.1M NaCl and 1mM DTT.

Stability

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles.

Purity

Greater than 90.0% as determined by SDS-PAGE.

Amino acid sequence

MGSSHHHHHH SSGLVPRGSH MAEGSPGTPD ESTPPPRKKK KDIRDYNDAD MARLLEQWEK DDDIEEGDLP EHKRPSAPVD FSKIDPSKPE SILKMTKKGK TLMMFVTVSG SPTEKETEEI TSLWQGSLFN ANYDVQRFIV GSDRAIFMLR DGSYAWEIKD FLVGQDRCAD VTLEGQVYPG KGGGSKEKNK TKQDKGKKKK EGDLKSRSSK EENRAGNKRE DL.

Usage

ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
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