- Name
- Description
- Cat#
- Pricings
- Quantity
Catalogue number
PRO-505
Synonyms
Protein fosB, G0/G1 switch regulatory protein 3, FOSB, G0S3, AP-1, GOS3, GOSB, MGC42291, DKFZp686C0818, FOS-B.
Introduction
Fos B encodes a nuclear protein of 338 amino acids which has 70% homology with c-Fos, exhibits similar kinetics of expression as c-Fos and forms heterodimers with both c-Jun and Jun B which bind to TRE DNA response elements. Functional homologs of c-Fos and Fos- B include Fra-1 and Fra-2 genes. The 4 members of Fos gene family are: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins which can dimerize with proteins of the JUN family, thus forming the transcription factor complex AP-1. The FOS proteins act as regulators of cell proliferation, differentiation, and transformation. Alternatively spliced transcript variants encoding different isoforms exist for Fos B.
Description
FOS-B Human Recombinant (a.a. 113-151) expressed in E.coli, shows a 32 kDa SDS-PAGE (Including GST).
The FOS-B is purified by proprietary chromatographic techniques.
The FOS-B is purified by proprietary chromatographic techniques.
Source
Escherichia Coli.
Physical Appearance
Sterile Filtered clear solution.
Formulation
FOS-B in 50mM Tris-Acetate, pH7.5, 1mM EDTA and 20% Glycerol.
Stability
Store vial at -20°C to -80°C. When stored at the recommended temperature, this protein is stable for 12 months.
Please prevent freeze-thaw cycles.
Please prevent freeze-thaw cycles.
Applications
• ELISA
• Inhibition Assays
• Western Blotting.
• Inhibition Assays
• Western Blotting.
Safety Data Sheet
Usage
Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.