Creatine kinase M-type, EC 220.127.116.11, Creatine kinase M chain, M-CK, CKM, CKMM.
The three isoenzymes (MM, MB, and BB) are found in muscle, cardiac and brain tissues. These recombinant proteins are ideal for calibrating diagnostic instruments and researching neuromuscular diseases. Creatine Kinases can be used for indications in many neuromuscular applications. These disorders include cardiac disease, mitochondrial disorders, inflammatory myopathies, myasthenia, polymyositis, McArdle''s disease, NMJ disorders, muscular dystrophy, ALS, hypo and hyperthyroid disorders, central core disease, acid maltase deficiency, myoglobinuria, rhabdomyolysis, motor neuron diseases, rheumatic diseases, and other that create elevated or reduced levels of Creatine Kinases.
Human CKM produced in Human Cardiac Tissues having a molecular mass of 82 kDa and PI 5.0-7.5. It’s the skeletal muscle specific creatine kinase and is elevated in case of strenuous exercise and in degenerative muscle disease.
Human Cardiac Tissues
Sterile Filtered clear solution.
The CKM protein solution is in 50mM Tris and 2mM DTT, pH 7.5 containing 50% Glycerol.
CKM although stable at 14°C for 1 week, should be stored at 2°-8°C.
Greater than 50.0%.
Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.