prospec

BEX1 Human

  • Name
  • Description
  • Pricings
  • Quantity
  • BEX1 Human
  • Brain Expressed X-Linked 1 Human Recombinant
  • Shipped with Ice Packs

Catalogue number

PRO-1530

Synonyms

BEX2, HBEX2, HGR74-h, Protein BEX1, Brain-expressed X-linked protein 1.

Introduction

Brain Expressed X-Linked 1 (BEX1) which participates in cell cycle progression and neuronal differentiation, is a signaling adapter molecule involved in p75NTR/NGFR signaling. BEX1 inhibits neuronal differentiation in response to nerve growth factor. BEX1 links between the cell cycle and neurotrophic factor signaling by acting as an upstream modulator of receptor signaling, adjusting biological responses to external signals with internal cellular states.

Description

BEX1 Human Recombinant produced in E. coli is a single polypeptide chain containing 148 amino acids (1-125) and having a molecular mass of 17.2kDa. BEX1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

Source

Escherichia Coli.

Physical Appearance

Sterile Filtered clear solution.

Formulation

The BEX1 solution (0.25mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.15M NaCl and 30% glycerol.

Stability

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles.

Purity

Greater than 80% as determined by SDS-PAGE.

Amino acid sequence

MGSSHHHHHH SSGLVPRGSH MGSMESKEKR AVNSLSMENA NQENEEKEQV ANKGEPLALP LDAGEYCVPR GNRRRFRVRQ PILQYRWDMM HRLGEPQARM REENMERIGE EVRQLMEKLR EKQLSHSLRA VSTDPPHHDH HDEFCLMP.

Usage

Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. They may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
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