prospec

WBP2 Human

  • Name
  • Description
  • Pricings
  • Quantity
  • WBP2 Human
  • WW Domain Binding Protein 2 Human Recombinant
  • Shipped with Ice Packs

Catalogue number

PRO-1208

Synonyms

WW domain binding protein 2, WBP-2.

Introduction

WW domain-binding protein 2 (WBP2) is a steroid hormone receptor coactivator, which contains 1 GRAM domain. The globular WW domain is comprised of 38-40 semiconserved amino acids shared by proteins of various functions including structural, regulatory, and signaling proteins. This domain is involved in mediating protein-protein interactions through the binding of polyproline ligands. WBP2 binds to the WW domain of Yes kinase-associated protein(YAP1) via its PY motifs.

Description

WBP2 Human Recombinant produced in E. coli is a single polypeptide chain containing 284 amino acids (1-261) and having a molecular mass of 30.5 kDa.
WBP2 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

Source

E.coli.

Physical Appearance

Sterile Filtered colorless solution.

Formulation

The WBP2 solution (0.5mg/1ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.1M NaCl, 1mM DTT and 20% glycerol.

Stability

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).

Avoid multiple freeze-thaw cycles.

Purity

Greater than 90% as determined by SDS-PAGE.

Amino acid sequence

MGSSHHHHHH SSGLVPRGSH MGSMALNKNH SEGGGVIVNN TESILMSYDH VELTFNDMKN VPEAFKGTKK GTVYLTPYRV IFLSKGKDAM QSFMMPFYLM KDCEIKQPVF GANYIKGTVK AEAGGGWEGS ASYKLTFTAG GAIEFGQRML QVASQASRGE VPSGAYGYSY MPSGAYVYPP PVANGMYPCP PGYPYPPPPP EFYPGPPMMD GAMGYVQPPP PPYPGPMEPP VSGPDVPSTP AAEAKAAEAA ASAYYNPGNP HNVYMPTSQP PPPPYYPPED KKTQ

Safety Data Sheet

Usage

ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
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