prospec

TSPAN7 Human

  • Name
  • Description
  • Pricings
  • Quantity
  • TSPAN7 Human
  • Tetraspanin 7 Human Recombinant
  • Shipped with Ice Packs

Catalogue number

PRO-2414

Synonyms

Tspan-7, Cell surface glycoprotein A15, Membrane component chromosome X surface marker 1, T-cell acute lymphoblastic leukemia-associated antigen 1, TALLA-1, Transmembrane 4 superfamily member 2, CD231, A15, DXS1692E, MXS1, TM4SF2.

Introduction

Tetraspanin 7, also known as TSPAN7, is part of the transmembrane 4 superfamily, which is also familiar as the tetraspanin family. Most of these proteins mediate signal transduction events which play a role in the regulation of cell development, activation, growth as well as motility. Furthermore, TSPAN7 is associated with X-linked mental retardation in addition to neuropsychiatric diseases such as Huntington's chorea, fragile X syndrome and myotonic dystrophy. Lately, TSPAN7 has been acknowledged as a key immune system target in type 1 diabetes.

Description

TSPAN7 Human Recombinant produced in Sf9 Insect cells is a single, glycosylated polypeptide chain containing 110 amino acids (113-213a.a.) and having a molecular mass of 12.6kDa. (Molecular size on SDS-PAGE under reducing conditions 13.5-18kDa). TSPAN7 is expressed with a 6amino acids His tag at C-Terminus and purified by proprietary chromatographic techniques.

Source

Sf9, Insect cells.

Physical Appearance

Sterile Filtered colorless solution.

Formulation

TSPAN7 protein solution (0.5mg/ml) contains Phosphate Buffered Saline (pH 7.4) and 10% glycerol.

Stability

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).

Avoid multiple freeze-thaw cycles.

Purity

Greater than 90.0% as determined by SDS-PAGE.

Amino acid sequence

ADPRHEIKDT FLRTYTDAMQ TYNGNDERSR AVDHVQRSLS CCGVQNYTNW STSPYFLEHG IPPSCCMNET DCNPQDLHNL TVAATKVNQK GCYDLVTSFM ETNMHHHHHH.

Usage

ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
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