prospec
TNFSF14 Human

TNFSF14 Human

  • Name
  • Description
  • Cat#
  • Pricings
  • Quantity
  • TNFSF14 Human

  • LIGHT Human Recombinant
  • CYT-1202
  • Shipped with Ice Packs

Catalogue number

CYT-1202

Synonyms

Tumor necrosis factor ligand superfamily member 14, CD258, Tnfsf14, Light

Introduction

TNFRSF14, a member of the TNF receptor superfamily, is a type I transmembrane protein. TNFRSF14 is expressed in peripheral blood T cells, B cells, monocytes and in various tissues enriched in lymphoid cells. TNFRSF14 operates as a co-stimulatory factor for the activation of lymphoid cells and as a deterrent to infection by herpesvirus. Additionally, TNFRSF14 encourages the proliferation of T cells, and triggers apoptosis of various tumor cells.

Description

Recombinant Human LIGHT (74-240 aa) having a Mw of 43kDa was purified from E. coli.
The Recombinant Human LIGHT is fused to GST tag at its N terminal and purified by proprietary chromatographic technique.

Source

Escherichia Coli.

Physical Appearance

Sterile Filtered clear solution.

Formulation

TNFSF14 solution contains 25mM Tris-Base/ 25mM K2CO3.

Stability

Store at 4°C if entire vial will be used within 2-4 weeks.
Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles.

Amino acid sequence

DGPAGSWEQL IQERRSHEVN PAAHLTGANS SLTGSGGPLL WETQLGLAFL RGLSYHDGAL VVTKAGYYYI YSKVQLGGVG CPLGLASTIT HGLYKRTPRY PEELELLVSQ QSPCGRATSS SRVWWDSSFL GGVVHLEAGE KVVVRVLDER LVRLRDGTRS YFGAFMV

Purity

Protein is >95% pure as determined by 10% PAGE (coomassie staining).

Applications

Immunoassay.

Safety Data Sheet

Usage

ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
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