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2 results found for “CD99”
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Name :
CD99 HumanDescription:
CD99 Human Recombinant
CD99 antigen, T-cell surface glycoprotein E2, E2 antigen, Protein MIC2, 12E7, CD99, MIC2, MIC2X, MIC2Y.
Product # :
PRO-2444Price :
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Shipped with Ice Packs
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Description
CD99 Human Recombinant produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 342 amino acids (23-122a.a.) and having a molecular mass of 37.3kDa (Molecular size on SDS-PAGE will appear at approximately 40-57kDa).CD99 is expressed with a 239 amino acids hIgG-His tag at C-Terminus and purified by proprietary chromatographic techniques.
Source
Sf9, Baculovirus cells.
Formulation
CD99 protein solution (1mg/ml) contains Phosphate Buffered Saline (pH 7.4) and 10% glycerol.
Purity
Greater than 95.0% as determined by SDS-PAGE.
Citations
More Info
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Introduction
CD99, or MIC2 gene product, or E2 antigen is expressed on the cell membrane of some lymphocytes, cortical thymocytes, and granulosa cells of the ovary. The antigen is also expressed by most pancreatic islet cells, Sertoli cells of the testis, and some endothelial cells. Mature granulocytes express very little or no CD99. MIC2 is strongly expressed on Ewing’s sarcoma cells and primitive peripheral neuroectodermal tumors.
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Synonyms
CD99 antigen, T-cell surface glycoprotein E2, E2 antigen, Protein MIC2, 12E7, CD99, MIC2, MIC2X, MIC2Y.
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Physical Appearance
Sterile filtered colorless solution.
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Stability
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
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Amino Acid Sequence
ADPDGGFDLS DALPDNENKK PTAIPKKPSA GDDFDLGDAV VDGENDDPRP PNPPKPMPNP NPNHPSSSGS FSDADLADGV SGGEGKGGSD GGGSHRKEGE EADLEPKSCD KTHTCPPCPA PELLGGPSVF LFPPKPKDTL MISRTPEVTC VVVDVSHEDP EVKFNWYVDG VEVHNAKTKP REEQYNSTYR VVSVLTVLHQ DWLNGKEYKC KVSNKALPAP IEKTISKAKG QPREPQVYTL PPSRDELTKN QVSLTCLVKG FYPSDIAVEW ESNGQPENNY KTTPPVLDSD GSFFLYSKLT VDKSRWQQGN VFSCSVMHEA LHNHYTQKSL SLSPGKHHHH HH.
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
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Name :
CD99L2 MouseDescription:
CD99 Molecule Like 2 Mouse Recombinant
CD99 antigen-like protein 2, MIC2-like protein 1, Cd99l2, Mic2l1, CD99 antigen-like protein 2 isoform 1, Xap89, Mic2l1.
Product # :
PRO-2780Price :
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Shipped with Ice Packs
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Description
CD99L2 Mouse Recombinant produced in HEK293 Cells is a single, glycosylated polypeptide chain containing 378 amino acids (26-161a.a) and having a molecular mass of 41.8kDa. CD99L2 is fused to a 239 amino acid hIgG-His tag at C-Terminus and purified by proprietary chromatographic techniques.
Source
HEK293 Cells.
Formulation
The CD99L2 solution (1mg/1ml) contains phosphate buffered saline (pH7.4) and 10% glycerol.
Purity
Greater than 90.0% as determined by SDS-PAGE.
Citations
More Info
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Synonyms
CD99 antigen-like protein 2, MIC2-like protein 1, Cd99l2, Mic2l1, CD99 antigen-like protein 2 isoform 1, Xap89, Mic2l1.
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Physical Appearance
Sterile filtered colorless solution.
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Stability
Store at 4°C if entire vial will be used within 2-4 weeks.Store, frozen at -20°C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
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Amino Acid Sequence
DGSDTDGFNL EDALKETSSV KQRWDHFSTT TRRPVTTRAP ANPAERWDHV ATTTTRRPGT TRAPSNPMEL DGFDLEDALD DRNDLDGPKK PSAGEAGGWS DKDLEDIVEG GGYKPDKNKG GGGYGSNDDP GSGISTETGLEPKSCDKTHT CPPCPAPELL GGPSVFLFPP KPKDTLMISR TPEVTCVVVD VSHEDPEVKF NWYVDGVEVH NAKTKPREEQ YNSTYRVVSV LTVLHQDWLN GKEYKCKVSN KALPAPIEKT ISKAKGQPRE PQVYTLPPSR DELTKNQVSL TCLVKGFYPS DIAVEWESNG QPENNYKTTP PVLDSDGSFF LYSKLTVDKS RWQQGNVFSC SVMHEALHNH YTQKSLSLSP GKHHHHHH.
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Background
The CD99L2 human recombinant, a variant of the CD99L2 protein, has gained substantial attention in biomedical research due to its intriguing molecular characteristics and potential implications in various biological processes. CD99L2, a member of the CD99 family of proteins, plays diverse roles in cellular adhesion, migration, and signal transduction. The CD99L2 human recombinant, generated through recombinant DNA technology, offers a valuable tool for investigating the intricate functions and therapeutic potential of this protein.
Understanding the molecular characteristics of CD99L2 is pivotal in unraveling its functional significance. CD99L2 belongs to the immunoglobulin superfamily and is primarily expressed on the cell surface. It exhibits unique structural features, including extracellular immunoglobulin-like domains and intracellular signaling motifs. These characteristics contribute to the complexity of CD99L2 and its ability to interact with various cellular components and modulate signaling pathways.
CD99L2 plays diverse roles in different physiological contexts. It is involved in cellular adhesion processes, regulating cell-cell interactions and migration in various tissues. Additionally, CD99L2 has been implicated in immune responses, particularly in the modulation of T-cell activation and leukocyte migration. The precise mechanisms underlying these functions are still being elucidated, highlighting the need for further investigation.
The CD99L2 human recombinant offers exciting prospects for research and therapeutic applications. By utilizing this recombinant protein, scientists can investigate the role of CD99L2 in disease pathogenesis, explore its interactions with other molecules, and potentially develop targeted therapies. CD99L2 has been implicated in cancer progression, immune disorders, and neurodevelopmental conditions, making it a promising candidate for novel therapeutic interventions.
This research aims to provide a comprehensive analysis of the CD99L2 human recombinant, focusing on its molecular characteristics, biological roles, and potential therapeutic implications. By shedding light on the intricate nature of CD99L2, we aim to contribute to a deeper understanding of its functional significance and pave the way for future research and therapeutic advancements.
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.