SARS Coronavirus is an enveloped virus containing three outer structural proteins, namely the membrane (M), envelope (E), and spike (S) proteins. Spike (S)-glycoprotein of the virus interacts with a cellular receptor and mediates membrane fusion to allow viral entry into susceptible target cells. Accordingly, S-protein plays an important role in virus infection cycle and is the primary target of neutralizing antibodies.
The HEK293 derived recombinant protein contains the SARS Coronavirus Spike S1 Gycoprotein, amino acids 14-667 fused to His tag at C-terminal.
Purified by immobilized metal affinity chromatographic technique.
SARS Spike S1 glycoprotein is lyophilized from 1x PBS pH-7.4 + 10% Glycerol.
Protein is shipped on ice packs. Upon arrival, Store at -20°C.
Measured by its binding ability in a functional ELISA with Human ACE-2 (CAT# enz-1125)
Protein is >90% pure as determined SDS-PAGE.