Ribonuclease, RNase A Family, 7, Skin-Derived
Antimicrobial Protein 2, RNase 7, SAP-2,
EC 220.127.116.11, EC 3.1.27., EC 3.1.27, Ribonuclease 7.
Ribonuclease 7 (RNASE7) is one of the final RNase A superfamily ribonucleases. RNASE7 was isolated from skin-derived stratum corneum. RNASE7 protein demonstrated potent ribonuclease activity and hence may contribute to the well-known ribonuclease activity of human skin. RNASE7 has revealed a broad spectrum antimicrobial activity against many pathogenic microorganisms and extraordinarily potent activity.
RNASE7 Human Recombinant produced in E.Coli is a single,
non-glycosylated polypeptide chain containing 151 amino acids (29-156 a.a) and
having a molecular mass of 16.9kDa.
RNASE7 is fused to a 23
amino acid His-tag at N-terminus & purified by proprietary chromatographic
Sterile Filtered colorless solution.
RNASE7 protein solution (0.5mg/ml) containing 20mM
Tris-HCl buffer (pH8.0) and 10% glycerol 1mM DTT.
Store at 4°C if entire vial will be used within 2-4 weeks.
Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles.
Greater than 90% as determined by SDS-PAGE.
Amino acid sequence
SSGLVPRGSH MGSKPKGMTS SQWFKIQHMQ PSPQACNSAM KNINKHTKRC KDLNTFLHEP
FSSVAATCQT PKIACKNGDK NCHQSHGPVS LTMCKLTSGK YPNCRYKEKR QNKSYVVACK PPQKKDSQQF
Safety Data Sheet
Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.