Retinoic acid receptor responder protein 1 isoform 1, TIG1, Retinoic acid receptor responder protein 1, RAR-responsive protein TIG1, RARRES1, Recombinant Human Retinoic Acid Receptor Responder 1.
Retinoic Acid Receptor Responder 1 (RARRES1) is a part of the TIGs family. TIGs operate like tumor suppressor genes in human cancers and are greatly expressed in skin, hair follicles and endothelial cells plus in pancreas, spleen and intestine. TIGs are growth regulators which mediate the growth suppressive effects of retinoids.
RARRES1 Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 275 amino acids (43-294) and having a molecular mass of 31.3 kDa.
RARRES1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Sterile Filtered colorless solution.
The RARRES1 solution (0.5mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.4M Urea and 10% glycerol.
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles.
Greater than 90.0% as determined by SDS-PAGE.
Amino acid sequence
MGSSHHHHHH SSGLVPRGSH MGSPDDPGQP QDAGVPRRLL QQAARAALHF FNFRSGSPSA LRVLAEVQEG RAWINPKEGC KVHVVFSTER YNPESLLQEG EGRLGKCSAR VFFKNQKPRP TINVTCTRLI EKKKRQQEDY LLYKQMKQLK NPLEIVSIPD NHGHIDPSLR LIWDLAFLGS SYVMWEMTTQ VSHYYLAQLT SVRQWKTNDD TIDFDYTVLL HELSTQEIIP CRIHLVWYPG KPLKVKYHCQ ELQTPEEASG TEEGSAVVPT ELSNF.
Safety Data Sheet
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.