prospec

RAB24 Human

  • Name
  • Description
  • Pricings
  • Quantity
  • RAB24 Human
  • RAB24, Member RAS Oncogene Family Human Recombinant
  • Shipped with Ice Packs

Catalogue number

PRO-951

Synonyms

RAB24 member RAS oncogene family, ras-related protein Rab-24.

Introduction

RAB24 is a member of the small GTPase superfamily which regulates intracellular protein transferring, nonetheless the specific role of RAB24 has not yet been revealed. RAB24 is distributed in the endoplasmic reticulum/cis-Golgi region and on late endosomal structures which suggests connection to autophagy-related courses. RAB24 demonstrates uncommon characteristics such as low intrinsic GTPase activity, and is incompetently prenylated when compared with other Rab proteins indicates that RAB24 has a distinctive part in the degradation of misfolded cellular proteins or trafficking of proteins to the nuclear envelope.

Description

RAB24 Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 227 amino acids (1-203) and having a molecular mass of 25.7 kDa.
RAB24 is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

Source

E.coli.

Physical Appearance

Sterile Filtered colorless solution.

Formulation

The RAB24 solution (0.5mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 2mM DTT, 0.1M NaCl, 0.1M EDTA and 30% glycerol.

Stability

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).

Avoid multiple freeze-thaw cycles.

Purity

Greater than 90% as determined by SDS-PAGE.

Amino acid sequence

MGSSHHHHHH SSGLVPRGSH MGSHMSGQRV DVKVVMLGKE YVGKTSLVER YVHDRFLVGP YQNTIGAAFV AKVMSVGDRT VTLGIWDTAG SERYEAMSRI YYRGAKAAIV CYDLTDSSSF ERAKFWVKEL RSLEEGCQIY LCGTKSDLLE EDRRRRRVDF HDVQDYADNI KAQLFETSSK TGQSVDELFQ KVAEDYVSVA AFQVMTEDKG VDLGQKPNPY FYSCCHH

Safety Data Sheet

Usage

ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
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