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PTPN4 Human

PTPN4 Human

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  • PTPN4 Human

  • Protein Tyrosine Phosphatase Non Receptor Type-4 Human Recombinant
  • PKA-075
  • Shipped with Ice Packs

Catalogue number

PKA-075

Synonyms

Protein Tyrosine Phosphatase, Non-Receptor Type 4 (Megakaryocyte), Protein-Tyrosine Phosphatase MEG1, PTPase-MEG1, EC 3.1.3.48, MEG, Tyrosine-Protein Phosphatase Non-Receptor Type 4, Megakaryocyte Protein-Tyrosine Phosphatase, Protein Tyrosine Phosphatase MEG1, Megakaryocyte Phosphatase, PTPMEG1, PTPMEG, Tyrosine-protein phosphatase non-receptor type 4, Protein-tyrosine phosphatase MEG1.

Introduction

Protein Tyrosine Phosphatase Non Receptor Type-4, also known as PTPN4 belongs to the protein tyrosine phosphatase, PTP family. PTPs are identified as signaling molecules which regulate a variety of cellular processes as well as cell growth, differentiation, mitotic cycle, and oncogenic transformation. PTPN4 is broadly expressed non-receptor protein tyrosine phosphatase. In addition, PTPN4 interacts with glutamate receptor delta 2 & epsilon, and affects glutamate receptors signaling and/or in regulation of their activities through tyrosine dephosphorylation.

Description

PTPN4 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 280 amino acids (655-913 a.a) and having a molecular mass of 32kDa.
PTPN4 is fused to a 21 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

Source

E.coli.

Physical Appearance

Sterile Filtered colorless solution.

Formulation

PTPN4 protein solution (1mg/ml) containing 20mM Tris buffer (pH 8.0) and 10% glycerol.

Stability

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles.

Purity

Greater than 85% as determined by SDS-PAGE.

Amino acid sequence

MGSSHHHHHH SSGLVPRGSH MVLTQFDQLY RKKPGMTMSC AKLPQNISKN RYRDISPYDA TRVILKGNED YINANYINME IPSSSIINQY IACQGPLPHT CTDFWQMTWE QGSSMVVMLT TQVERGRVKC HQYWPEPTGS SSYGCYQVTC HSEEGNTAYI FRKMTLFNQE KNESRPLTQI QYIAWPDHGV PDDSSDFLDF VCHVRNKRAG KEEPVVVHCS AGIGRTGVLI TMETAMCLIE CNQPVYPLDI VRTMRDQRAM MIQTPSQYRF VCEAILKVYE.

Safety Data Sheet

SDS

Usage

ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
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