About PVALB / Parvalbumin Protein:
PVALB is a protein found in the brain. It was first discovered in 1977 by Dr. Alois Alzheimer and named after him to honor his work on the disease of the same name.
The three primary functions of this protein are:
●Calcium ion homeostasis
PVALB plays a vital role in neuron function because it helps protect cells from oxidative stress and regulates synaptic transmission at synapses where neurons communicate with each other.
Mechanism of PVALB
The protein that makes up PVALB is attached to the membrane of a neuron. The function of this protein is to bind and transport calcium ions in an environment where there are high concentrations.
This use helps provide stability when too many calcium ions are present, such as after an influx of extracellular ion release caused by neuronal transmission.
PVALB is one of many proteins that make up the endoplasmic reticulum membrane. They help regulate calcium ion homeostasis by maintaining a balance between extracellular and intracellular levels, which helps in neuron function and synaptic transmission.
It is also an essential part of neuroprotection because it protects neurons from oxidative stress caused by free radicals.
Importance of Parvalbumin Protein
The importance of PVALB is that it helps regulate calcium ion levels in neurons, making sure there is a balance between the amount inside and outside the neuron.
It also protects neuronal cells from oxidative stress caused by free radicals and regulates synaptic transmission at synapses where neurons communicate with each other.
In conclusion, PVALB is an essential protein that regulates calcium ion levels in neurons, protecting them from oxidative stress and controlling synaptic transmission.