Mouse Antibody Monoclonal.
p53 is a tumor suppressor gene expressed in a wide variety of tissue types and is involved in regulating cell growth, replication, and apoptosis. It binds to mdm2, SV40 T antigen and human papilloma virus E6 protein p53 senses DNA damage and possibly facilitating repair. Mutation involving p53 is found in a wide variety of malignant tumors, including breast, ovarian, bladder, colon, lung, and melanoma.
Monoclonal antibodies are produced by immunizing mouse with full length His-tagged p53 protein.
Sterile Filtered solution.
1×PBS & 50% glycerol.
Western Blotting: 2μg/ml.
Western Blot, Immunoprecipitation.
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