prospec

MAPK8 Human

  • Name
  • Description
  • Pricings
  • Quantity
  • MAPK8 Human
  • Mitogen-Activated Protein Kinase 8 Human Recombinant
  • Shipped with Ice Packs

Catalogue number

PKA-080

Synonyms

Mitogen-activated protein kinase 8, MAPK8, MAP kinase 8, MAPK 8, JNK-46, Stress-activated protein kinase 1c, SAPK1c, Stress-activated protein kinase JNK1, c-Jun N-terminal kinase 1, JNK1, PRKM8, SAPK1, SAPK1C, Mitogen-activated protein kinase 8 JNK beta 2, JNK, JNK1A2, JNK21B1/2.

Introduction

Mitogen-Activated Protein Kinase 8, also known as MAPK8, is a part of the MAP kinase family. MAP kinases an integration point for multiple biochemical signals which take part in a various cellular processes. MAPK8 is a protein coding gene which is also involved in UV radiation induced apoptosis that is associated to cytochrom c-mediated cell death pathway.

Description

MAPK8 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 450 amino acids (1-427a.a) and having a molecular mass of 50.5kDa.
MAPK8 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

Source

E.coli.

Physical Appearance

Sterile Filtered colorless solution.

Formulation

MAPK8 solution (0.5mg/ml) contains Phosphate Buffer Saline (pH7.4), 20% glycerol and 1mM DTT.

Stability

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).

Avoid multiple freeze-thaw cycles.

Purity

Greater than 85% as determined by SDS-PAGE.

Amino acid sequence

MGSSHHHHHH SSGLVPRGSH MGSMSRSKRD NNFYSVEIGD STFTVLKRYQ NLKPIGSGAQ GIVCAAYDAI LERNVAIKKL SRPFQNQTHA KRAYRELVLM KCVNHKNIIG LLNVFTPQKS LEEFQDVYIV MELMDANLCQ VIQMELDHER MSYLLYQMLC GIKHLHSAGI IHRDLKPSNI VVKSDCTLKI LDFGLARTAG TSFMMTPYVV TRYYRAPEVI LGMGYKENVD IWSVGCIMGE MIKGGVLFPG TDHIDQWNKV IEQLGTPCPE FMKKLQPTVR TYVENRPKYA GYSFEKLFPD VLFPADSEHN KLKASQARDL LSKMLVIDAS KRISVDEALQ HPYINVWYDP SEAEAPPPKI PDKQLDEREH TIEEWKELIY KEVMDLEERT KNGVIRGQPS PLGAAVINGS QHPSSSSSVN DVSSMSTDPT LASDTDSSLE AAAGPLGCCR.

Safety Data Sheet

Usage

ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Back to Top