prospec

LCP2 Human

  • Name
  • Description
  • Pricings
  • Quantity
  • LCP2 Human
  • Lymphocyte Cytosolic Protein 2 Human Recombinant
  • Shipped with Ice Packs

Catalogue number

PRO-2500

Synonyms

Lymphocyte Cytosolic Protein 2, SH2 Domain-Containing Leukocyte Protein Of 76 KDa, 76 KDa Tyrosine Phosphoprotein, SLP-76 Tyrosine Phosphoprotein, SLP76, Lymphocyte Cytosolic Protein 2 (SH2 Domain Containing Leukocyte Protein Of 76kDa), Lymphocyte Cytosolic Protein 2 (SH2 Domain-Containing Leukocyte Protein Of 76kD), SH2 Domain-Containing Leukocyte Protein Of 76Kd, SLP-76, LCP2.

Introduction

LCP2 (lymphocyte cytosolic protein 2) is an intracellular docking protein with a single SH2 recognition domain. LCP2 is implicated in T-cell antigen receptor mediated signaling. Moreover, LCP2 is phosphorylated by ZAP70 which leads to NF-AT as well as IL2 gene activation. B Cell Linker Protein Deficiency is one of the associated diseases with LCP2.

Description

LCP2 produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain (1-533 a.a.) and fused to a 6 aa His Tag at C-terminus containing a total of 542 amino acids and having a molecular mass of 61.2kDa.
LCP2 shows multiple bands between 70-100kDa on SDS-PAGE, reducing conditions and purified by proprietary chromatographic techniques.

Source

Sf9, Baculovirus cells.

Physical Appearance

Sterile Filtered colorless solution.

Formulation

LCP2 protein solution (0.25mg/ml) contains 10% glycerol & Phosphate buffered saline (pH7.4).

Stability

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles.

Purity

Greater than 90.0% as determined by SDS-PAGE.

Amino acid sequence

ADPMALRNVP FRSEVLGWDP DSLADYFKKL NYKDCEKAVK KYHIDGARFL NLTENDIQKF PKLRVPILSK LSQEINKNEE RRSIFTRKPQ VPRFPEETES HEEDNGGWSS FEEDDYESPN DDQDGEDDGD YESPNEEEEA PVEDDADYEP PPSNDEEALQ NSILPAKPFP NSNSMYIDRP PSGKTPQQPP VPPQRPMAAL PPPPAGRNHS PLPPPQTNHE EPSRSRNHKT AKLPAPSIDR STKPPLDRSL APFDREPFTL GKKPPFSDKP SIPAGRSLGE HLPKIQKPPL PPTTERHERS SPLPGKKPPV PKHGWGPDRR ENDEDDVHQR PLPQPALLPM SSNTFPSRST KPSPMNPLPS SHMPGAFSES NSSFPQSASL PPYFSQGPSN RPPIRAEGRN FPLPLPNKPR PPSPAEEENS LNEEWYVSYI TRPEAEAALR KINQDGTFLV RDSSKKTTTN PYVLMVLYKD KVYNIQIRYQ KESQVYLLGT GLRGKEDFLS VSDIIDYFRK MPLLLIDGKN RGSRYQCTLT HAAGYPHHHH HH

Safety Data Sheet

Usage

ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
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