prospec

JAM2 Human, Sf9

  • Name
  • Description
  • Pricings
  • Quantity
  • JAM2 Human, Sf9
  • Junctional Adhesion Molecule 2 Human Recombinant, Sf9
  • Shipped with Ice Packs

Catalogue number

PRO-2509

Synonyms

Junctional Adhesion Molecule 2, Vascular Endothelial Junction-Associated Molecule, C21orf43, VE-JAM, JAM-2, JAM-B, VEJAM, Junctional Adhesion Molecule B, JAM-IT/VE-JAM, CD322 Antigen, PRO245, CD322, JAMB, Junctional adhesion molecule B.

Introduction

Junctional Adhesion Molecule 2 (JAM2) is a member of the immunoglobulin superfamily, and the junctional adhesion molecule (JAM) family. JAM2 is a type I membrane protein which is localized at the tight junctions of both epithelial and endothelial cells. JAM2 functions as an adhesive ligand for interacting with various immune cell types, and may have a role in lymphocyte homing to secondary lymphoid organs.

Description

JAM2 produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 452 amino acids (29-238a.a.) and having a molecular mass of 50.7kDa. (Molecular size on SDS-PAGE will appear at approximately 50-70kDa).
JAM2 is expressed with a 239 amino acid hIgG-His-tag at C-Terminus and purified by proprietary chromatographic techniques.

Source

Sf9, Baculovirus cells.

Physical Appearance

Sterile Filtered colorless solution.

Formulation

JAM2 protein solution (0.5mg/ml) contains 50% glycerol, 1mM DTT & Phosphate Buffered Saline (pH 7.4).

Stability

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles.

Purity

Greater than 90.0% as determined by SDS-PAGE.

Amino acid sequence

ADPFSAPKDQ QVVTAVEYQE AILACKTPKK TVSSRLEWKK LGRSVSFVYY QQTLQGDFKN RAEMIDFNIR IKNVTRSDAG KYRCEVSAPS EQGQNLEEDT VTLEVLVAPA VPSCEVPSSA LSGTVVELRC QDKEGNPAPE YTWFKDGIRL LENPRLGSQS TNSSYTMNTK TGTLQFNTVS KLDTGEYSCE ARNSVGYRRC PGKRMQVDDL NISLEPKSCD KTHTCPPCPA PELLGGPSVF LFPPKPKDTL MISRTPEVTC VVVDVSHEDP EVKFNWYVDG VEVHNAKTKP REEQYNSTYR VVSVLTVLHQ DWLNGKEYKC KVSNKALPAP IEKTISKAKG QPREPQVYTL PPSRDELTKN QVSLTCLVKG FYPSDIAVEW ESNGQPENNY KTTPPVLDSD GSFFLYSKLT VDKSRWQQGN VFSCSVMHEA LHNHYTQKSL SLSPGKHHHH HH.

Usage

ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
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