prospec
IL34 Human

IL34 Human

  • Name
  • Description
  • Cat#
  • Pricings
  • Quantity
  • IL34 Human

  • Interleukin 34 Human Recombinant
  • CYT-042
  • Shipped with Ice Packs

Catalogue number

CYT-042

Synonyms

Interleukin 34, C16orf77, MGC34647, IL34.

Introduction

Interleukin 34 (IL34) is a cytokine that promotes the differentiation and viability of monocytes and macrophages through the colony-stimulating factor-1 receptor and is a part of a group of cytokines called interleukins. IL34 increases growth or survival of immune cells known as monocytes. IL34 protein obtains its activity by binding the Colony stimulating factor 1 receptor. Interleukin 34 has also a potential part in viral infection, the adaptive immune response and bone marrow cell proliferation. Furthermore, IL34 plays an important role in innate immunity and in inflammatory processes.

Description

IL34 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 260 amino acids (21-242 a.a) and having a molecular mass of 29.6kDa. IL34 is fused to a 38 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

Source

E.coli.

Physical Appearance

Sterile Filtered colorless solution.

Formulation

The IL34 solution (1mg/1ml) contains 20mM Tris-HCl buffer (pH8.0), 10% glycerol and 0.4M Urea.

Stability

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles.

Purity

Greater than 85% as determined by SDS-PAGE.

Amino acid sequence

MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSHMNE PLEMWPLTQN EECTVTGFLR DKLQYRSRLQ YMKHYFPINY KISVPYEGVF RIANVTRLQR AQVSERELRY LWVLVSLSAT ESVQDVLLEG HPSWKYLQEV QTLLLNVQQG LTDVEVSPKV ESVLSLLNAP GPNLKLVRPK ALLDNCFRVM ELLYCSCCKQ SSVLNWQDCE VPSPQSCSPE PSLQYAATQL YPPPPWSPSS PPHSTGSVRP VRAQGEGLLP.

Safety Data Sheet

Usage

ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
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