prospec
IGHG2A Mouse

IGHG2A Mouse

  • Name
  • Description
  • Cat#
  • Pricings
  • Quantity
  • IGHG2A Mouse

  • Ig gamma-2A chain C region Mouse Recombinant
  • PRO-2842
  • Shipped with Ice Packs

Catalogue number

PRO-2842

Synonyms

Immunoglobulin heavy chain constant region gamma 2a, Immunoglobulin G, Ig gamma-2A chain C region, A allele, Ighg.

Description

IGHG2A Mouse Recombinant produced inSf9 Baculovirus cells is a single glycosylated polypeptide chain containing 242 amino acids (98-330 a.a.) and having a molecular mass of 27.5 kDa. IGHG2A Mouse is fused to a 6 amino acid His-tag at C-terminus & purified by proprietary chromatographic techniques.

Source

Sf9, Baculovirus cells.

Physical Appearance

Sterile filtered colorless solution.

Formulation

IGHG2A protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH 8.0) and 10% glycerol.

Stability

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).

Avoid multiple freeze-thaw cycles.

Purity

Greater than 90.0% as determined by SDS-PAGE.

Amino acid sequence

ADPEPRGPTI KPCPPCKCPA PNLLGGPSVF IFPPKIKDVL MISLSPIVTC VVVDVSEDDP DVQISWFVNN VEVHTAQTQT HREDYNSTLR VVSALPIQHQ DWMSGKEFKC KVNNKDLPAP IERTISKPKG SVRAPQVYVL PPPEEEMTKK QVTLTCMVTD FMPEDIYVEW TNNGKTELNY KNTEPVLDSD GSYFMYSKLR VEKKNWVERN SYSCSVVHEG LHNHHTTKSF SRTPGKHHHH HH.

Safety Data Sheet

Usage

ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

Background

The Ig gamma-2A chain C region is the constant region of the gamma-2A heavy chain in immunoglobulin molecules, particularly in mice. This region is responsible for various effector functions of IgG2a antibodies, such as antibody-dependent cellular cytotoxicity and phagocytosis and is encoded by the Ighg2a gene. The constant region of the gamma-2A chain takes part in various immune response such as regulation of the immune response, antibody-dependent cellular cytotoxicity and phagocytosis.

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