prospec

HCV Core Antibody

  • Name
  • Description
  • Pricings
  • Quantity
  • HCV Core Antibody
  • Hepatitis C Virus Core, Mouse antibody
  • Shipped at Room temp.

Catalogue number

ANT-286

Type

Mouse antibody Monoclonal.

Introduction

HCV is a small 50nm, enveloped, single-stranded, positive sense RNA virus in the family Flaviviridae.
HCV has a high rate of replication with approximately one trillion particles produced each day in an infected individual. Due to lack of proofreading by the HCV RNA polymerase, the HCV has an exceptionally high mutation rate, a factor that may help it elude the host's immune response. Hepatitis C virus is classified into six genotypes (1-6) with several subtypes within each genotype. The preponderance and distribution of HCV genotypes varies globally. Genotype is clinically important in determining potential response to interferon-based therapy and the required duration of such therapy. Genotypes 1 and 4 are less responsive to interferon-based treatment than are the other genotypes (2, 3, 5 and 6).

Immunogen

Recombinant HCV peptide Mix.

Ig Subclass

Mouse IgG1.

Source

Protein-A.

Clone

NYRHepC.

Formulation

1mg/ml in PBS (After Reconstitution).

Shipping Conditions

Shipped lyophilized at ambient Temperature.

Stability

In lyophilized form, for long periods, store at 4°C in a dry environment. After reconstitution, if not intended for use within a month, aliquot and store at -20°C.

Solubility

Reconstitute with H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use.

Titer

By direct ELISA, 1:10,000 dilution will yield 0.5 O.D using alkaline phosphatase conjugated rabbit anti-mouse Ig (Jackson Laboratories).

Applications

Direct ELISA, Western Blot, Immuneprecipitation, immunohistochemistry.

Safety Data Sheet

Usage

ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
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