FOLR2 Human

FOLR2 Human

Folate Receptor

Name

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  • Name :

    FOLR2 Human

    Description:

    Folate Receptor 2 Human Recombinant

    Folate receptor beta, FR-beta, Folate receptor 2, Folate receptor, fetal/placental, Placental folate-binding protein, BETA-HFR Protein, FBP/PL-1 Protein, FR-BETA Protein, FR-P3 Protein, FRbeta, FR-BETA, FBP/PL1, BETA-HFR, FBP, FOLR2

    Product # :

    PRO-2673

    Price :

    Quantity :

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  • description
  • source
  • formulation
  • purity
  • biological activity
  • More Info

Description

FOLR2 Human Recombinant is a single, glycosylated polypeptide chain containing 215 amino acids (22-230a.a) and having a molecular mass of 25.1kDa. FOLR2 is fused to a 6 a.a His tag at C-terminal, and is purified by proprietary chromatographic techniques.

Source

HEK293 Cells.

Formulation

The FOLR2 solution (0.25mg/ml) contains 10% glycerol and Phosphate-Buffered Saline (pH 7.4).

Purity

Greater than 90.0% as determined by SDS-PAGE.

Biological Activity

ED50 Range is ≤ 5 ug/ml. The Biological activity is measured by the protein’s binding ability in a functional ELISA with Folic Acid-BSA.

More Info

  • Introduction

    Folate Receptor 1, also known as FOLR1, is a part of the folate receptor family whose members bind folic acid. FOLR1 binds to folate and reduced folic acid derivatives and facilitates transfer of 5-methyltetrahydrofolate and folate analogs into the cells. FOLR1 is either attaches to membranes through a glycosyl-phosphatidylinositol linkage or exists in a soluble form. FOLR1 is also needed for embryonic development and normal cell proliferation.

  • Synonyms

    Folate receptor beta, FR-beta, Folate receptor 2, Folate receptor, fetal/placental, Placental folate-binding protein, BETA-HFR Protein, FBP/PL-1 Protein, FR-BETA Protein, FR-P3 Protein, FRbeta, FR-BETA, FBP/PL1, BETA-HFR, FBP, FOLR2

  • Physical Appearance

    Sterile Filtered colorless solution.

  • Stability

    Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.

  • Amino Acid Sequence

    QDRTDLLNVC MDAKHHKTKP GPEDKLHDQC SPWKKNACCT ASTSQELHKD TSRLYNFNWD HCGKMEPACK RHFIQDTCLY ECSPNLGPWI QQVNQSWRKE RFLDVPLCKE DCQRWWEDCH TSHTCKSNWH RGWDWTSGVN KCPAGALCRT FESYFPTPAA LCEGLWSHSY KVSNYSRGSG RCIQMWFDSA QGNPNEEVAR FYAAAMHVNH HHHHH

ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

Folr2 Human

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