prospec

CD23 Human, Sf9

  • Name
  • Description
  • Pricings
  • Quantity
  • CD23 Human, Sf9
  • CD23 Human Recombinant, Sf9
  • Shipped with Ice Packs

Catalogue number

PRO-2499

Synonyms

Low affinity immunoglobulin epsilon Fc receptor isoform a, BLAST-2, CD23, CD23A, CLEC4J, FCE2, IGEBF, C-type lectin domain family 4 member J, Immunoglobulin E-binding factor, Lymphocyte IgE receptor.

Introduction

FCER2, or Fc epsilon RII, is a receptor for IgE with low affinity, which is critical to regulation of IgE levels. IgE is an antibody isotype that attached to allergy and resistance to parasites. FCER2 is a C-type lectin, contrary to many of the receptors for antibodies. FCER2 is located on activated macrophages, mature B cells, follicular dendritic cells, platelets and eosinophils.

Description

FCER2 produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 283 amino acids (48-321a.a.) and having a molecular mass of 32.0kDa. (Molecular size on SDS-PAGE will appear at approximately 28-40kDa).
FCER2 is expressed with a 9 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques.

Source

Sf9, Baculovirus cells.

Physical Appearance

Sterile Filtered colorless solution.

Formulation

FCER2 protein solution (0.25mg/ml) contains phosphate buffered saline (pH7.4) and 10% glycerol.

Stability

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles.

Purity

Greater than 90.0% as determined by SDS-PAGE.

Amino acid sequence

ADPDTTQSLK QLEERAARNV SQVSKNLESH HGDQMAQKSQ STQISQELEE LRAEQQRLKS QDLELSWNLN GLQADLSSFK SQELNERNEA SDLLERLREE VTKLRMELQV SSGFVCNTCP EKWINFQRKC YYFGKGTKQW VHARYACDDM EGQLVSIHSP EEQDFLTKHA SHTGSWIGLR
NLDLKGEFIW VDGSHVDYSN WAPGEPTSRS QGEDCVMMRG SGRWNDAFCD RKLGAWVCDR LATCTPPASE GSAESMGPDS RPDPDGRLPT
PSAPLHSHHH HHH.

Safety Data Sheet

Usage

ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
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