prospec

ETS1 Human

  • Name
  • Description
  • Pricings
  • Quantity
  • ETS1 Human
  • C-ets-1 Protein Human Recombinant
  • Shipped with Ice Packs

Catalogue number

PRO-501

Synonyms

Protein C-ets-1, ETS-1, p54, ETS1, EWSR2, FLJ10768.

Introduction

The proto-oncogene c-Ets-1 is a transcription factor known to regulate expression of a number of genes involved in extracellular matrix remodeling, control numerous genes and are involved in stem cell development, cell senescence and death, and tumorigenesis. Ets-1 interacts with the urokinase-type plasminogen activator gene enhancer and with the promoters of stromelysins-1 and collagenase-1 gene which may implicate it in this process.
The conserved ETS domain inside these proteins is a winged helix-turn-helix DNA-binding domain that recognizes the core consensus DNA sequence GGAA/T of target genes.

Description

ETS1 Human Recombinant (aa 220-442) expressed in E.coli, shows a 48 kDa band on SDS-PAGE (Including GST).
The ETS1 is purified by proprietary chromatographic techniques.

Source

Escherichia Coli.

Physical Appearance

Sterile Filtered clear solution.

Formulation

ETS1 protein in 50mM Tris-Acetate, pH7.5, 1mM EDTA and 20% Glycerol.

Stability

Store vial at -20°C to -80°C. When stored at the recommended temperature, this protein is stable for 12 months.
Please prevent freeze-thaw cycles.

Applications

• ELISA
• Inhibition Assays
• Western Blotting.

Safety Data Sheet

Usage

Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
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