prospec
CoV-2 Spike E-Mosaic

CoV-2 Spike E-Mosaic

  • Name
  • Description
  • Cat#
  • Pricings
  • Quantity
  • CoV-2 Spike E-Mosaic

  • Coronavirus 2019 Spike E-Mosaic Recombinant
  • SARS-014
  • Shipped with Ice Packs

Catalogue number

SARS-014

Introduction

A human infecting coronavirus (viral pneumonia) called 2019 novel coronavirus, 2019-nCoV was found in the fish market at the city of Wuhan, Hubei province of China on December 2019.

The 2019-nCoV shares an 87% identity to the 2 bat-derived severe acute respiratory syndrome 2018 SARS-CoV-2 located in Zhoushan of eastern China. 2019-nCoV has an analogous receptor-BD-structure to that of 2018 SARS-CoV, even though there is a.a. diversity so thus the 2019-nCoV might bind to ACE2 receptor protein (angiotensin-converting enzyme 2)  in humans.

While bats are possibly the host of 2019-nCoV, researchers suspect that animal from the ocean sold at the seafood market was an intermediate host. RSCU analysis proposes that the 2019-nCoV is a recombinant within the viral spike glycoprotein between the bat coronavirus and an unknown coronavirus.

Description

The E.Coli derived recombinant protein contains the Coronavirus 2019 spike Envelope Mosaic immunodominant regions having a Mwq of 40.5 kDa, fused to 6xHis tag at C-terminal.

Source

Escherichia Coli.

Physical Appearance

Sterile Filtered clear solution.

Formulation

CoV 2019 Spike E-Mosaic Protein 1mg/ml solution is supplied in 1x PBS.

Stability

CoV 2019 Spike E-Mosaic Protein is shipped on ice packs. Upon arrival, Store at -20°C.

Purity

CoV 2019 Spike E-Mosaic Protein is >90% pure as determined SDS-PAGE.

Amino acid sequence

S-part (20-210 a.a.)

RTQLPPAYTN SFTRGVYYPD KVFRSSVLHS TQDLFLPFFS NVTWFHAIHV SGTNGTKRFD NPVLPFNDGV YFASTEKSNI IRGWIFGTTL DSKTQSLLIV NNATNVVIKV CEFQFCNDPF LGVYYHKNNK SWMESEFRVY SSANNCTFEY VSQPFLMDLE GKQGNFKNLR EFVFKNIDGY FKIYSKHTPI 

 

E-part (51-75 a.a.)

AYCCNIVNVS LVKPSFYVYS RVKNLNSSRV PDLLV 

 

M part (100-222 a.a.)

RLFARTRSMW SFNPETNILL NVPLHGTILT RPLLESELVI GAVILRGHLR IAGHHLGRCD
IKDLPKEITV ATSRTLSYYK LGASQRVAGD SGFAAYSRYR IGNYKLNTDH SSSSDNIALL VQ

Safety Data Sheet

Usage

ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
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